tag:blogger.com,1999:blog-55845309881321499612024-03-14T06:00:19.518+05:30Implant SutraSūtra (Sanskrit: sū́tra, Devanagari: सूत्र, Pāli: sutta), literally means a rope or thread that holds things together, and more metaphorically refers to an aphorism (or line, rule, formula), or a collection of such aphorisms in the form of a manual.Mathaihttp://www.blogger.com/profile/13394299451400249276noreply@blogger.comBlogger141125tag:blogger.com,1999:blog-5584530988132149961.post-84173713340789440552017-10-13T12:01:00.001+05:302017-10-13T12:01:30.306+05:30Innovative collagen matrix for soft-tissue generation announced at EAO 2017 | Dental Tribune International<a href="http://www.dental-tribune.com/articles/news/europe/36563_innovative_collagen_matrix_for_soft-tissue_generation_announced_at_eao_2017.html">Innovative collagen matrix for soft-tissue generation announced at EAO 2017 | Dental Tribune International</a>: <br /><br />
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<a href="https://chrome.google.com/webstore/detail/pengoopmcjnbflcjbmoeodbmoflcgjlk" style="font-size: 13px;">'via Blog this'</a>Mathaihttp://www.blogger.com/profile/13394299451400249276noreply@blogger.com0tag:blogger.com,1999:blog-5584530988132149961.post-35095494521881099632016-10-01T10:09:00.001+05:302016-10-01T10:09:46.917+05:30Bony biomaterial may keep kids from outgrowing their implants<a href="http://newatlas.com/elastic-ink-3d-printed-bone-implants/45692/?utm_source=Gizmag+Subscribers&utm_campaign=6f018cd0d1-UA-2235360-4&utm_medium=email&utm_term=0_65b67362bd-6f018cd0d1-76698122">Bony biomaterial may keep kids from outgrowing their implants</a>: <br /><br />
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<a href="https://chrome.google.com/webstore/detail/pengoopmcjnbflcjbmoeodbmoflcgjlk" style="font-size: 13px;">'via Blog this'</a>Mathaihttp://www.blogger.com/profile/13394299451400249276noreply@blogger.com0tag:blogger.com,1999:blog-5584530988132149961.post-4767684657398524692015-03-18T10:06:00.001+05:302015-03-18T10:06:32.918+05:30Grand Central Station for Dentists<a href="http://www.dentalcoffee.com/">Grand Central Station for Dentists</a>: <br /><br />
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<a href="https://chrome.google.com/webstore/detail/pengoopmcjnbflcjbmoeodbmoflcgjlk" style="font-size: 13px;">'via Blog this'</a>Mathaihttp://www.blogger.com/profile/13394299451400249276noreply@blogger.com0tag:blogger.com,1999:blog-5584530988132149961.post-4977466010057766352013-11-12T18:06:00.002+05:302013-11-12T18:06:48.186+05:30Dental Miscellany !<div dir="ltr" style="text-align: left;" trbidi="on">
For some dental miscellany check out<br />
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<a href="http://www.crookedbrains.net/2013/11/coolest-tooth-inspired-products-designs.html" target="_blank">http://www.crookedbrains.net/2013/11/coolest-tooth-inspired-products-designs.html</a><br />
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Thanks to Dr.Shirish Waghulde for this one !</div>
Mathaihttp://www.blogger.com/profile/13394299451400249276noreply@blogger.com0tag:blogger.com,1999:blog-5584530988132149961.post-29008933176039638252013-11-12T10:44:00.001+05:302013-11-12T10:44:02.071+05:30Bio Patch Regrows Bone<a href="http://www.drbicuspid.com/index.aspx?sec=sup&sub=rst&pag=dis&itemid=314613&wf=1697">Bio Patch regrows bone</a>: <br />
An interesting new development in bone engineering. Hopefully some of this technology will reach our clinics soon!<br />
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<a href="https://chrome.google.com/webstore/detail/pengoopmcjnbflcjbmoeodbmoflcgjlk" style="font-size: 13px;">'via Blog this'</a>Mathaihttp://www.blogger.com/profile/13394299451400249276noreply@blogger.com0tag:blogger.com,1999:blog-5584530988132149961.post-80519538654238667862013-10-07T20:02:00.001+05:302013-10-07T20:02:59.265+05:30Interesting Solution to the Flossing Problem !<a href="http://www.flossolution.com/" target="_blank"><img alt="#" src="http://www.flossolution.com/v/vspfiles/templates/posh/images/homepage/promo_right_top.jpg" /></a><br />
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<a href="https://chrome.google.com/webstore/detail/pengoopmcjnbflcjbmoeodbmoflcgjlk" style="font-size: 13px;">'via Blog this'</a>Mathaihttp://www.blogger.com/profile/13394299451400249276noreply@blogger.com0tag:blogger.com,1999:blog-5584530988132149961.post-51823445193756679912013-09-28T11:56:00.001+05:302013-09-28T11:56:32.944+05:30Hello ! Sorry for the long absence !<div dir="ltr" style="text-align: left;" trbidi="on">
Hello everybody and sorry for the long absence ! We've had some problems with spam and hacking in the Implant Sutra blog that forced me to take some time off. I'm back ! I'm grateful to all of you who continued to visit and who motivated me to get back to blogging .<br />
Thanks !</div>
Mathaihttp://www.blogger.com/profile/13394299451400249276noreply@blogger.com0tag:blogger.com,1999:blog-5584530988132149961.post-31588446116303032442012-12-21T11:21:00.001+05:302012-12-21T11:21:03.000+05:30Evidence insufficient to recommend routine antibiotics for joint replacement patients, experts say<a href="http://www.sciencedaily.com/releases/2012/12/121218121429.htm#.UNP4ZuIHTmw.blogger">Evidence insufficient to recommend routine antibiotics for joint replacement patients, experts say</a><br />
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Please read and save for future reference ! The latest recommendations for a commonly encountered clinical situation.Mathaihttp://www.blogger.com/profile/13394299451400249276noreply@blogger.com0tag:blogger.com,1999:blog-5584530988132149961.post-35056541181006060032012-12-12T22:38:00.001+05:302012-12-12T22:38:45.991+05:30How Videogames Could Help Train the Next Generation of Robotic Surgeons<b><i>From Wired</i></b><br />
<b><i>I wonder when robotic surgery will be a reality in dentistry! OMFS will most probably be the place it will make it's first impact. In the meantime I'm going to get started on my video games!</i></b><br />
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<a href="http://feeds.wired.com/~r/wired/index/~3/qH2b4Ur27KI/">How Videogames Could Help Train the Next Generation of Robotic Surgeons</a>: Doling out death in the virtual world of first-person-shooter games might help the next generation of surgeons save lives in the real world. A new study used simulators to compare the robotic surgery skills of med school residents against college and high school students who spend a lot of their time playing video games -- and the video gamers won.<img height="1" src="http://feeds.feedburner.com/~r/wired/index/~4/qH2b4Ur27KI" width="1" />Mathaihttp://www.blogger.com/profile/13394299451400249276noreply@blogger.com0tag:blogger.com,1999:blog-5584530988132149961.post-64116282401578260352012-12-07T12:11:00.001+05:302012-12-07T12:11:51.201+05:30Periodontist Group Develops Diabetes Educational Material<a href="http://www.thedentalgeek.com/2012/12/periodontist-group-develops-diabetes-educational-material/">Periodontist Group Develops Diabetes Educational Material</a>: In honor of November, American Diabetes Month, the New Jersey Society of Periodontists developed this great brochure that can help your patients understand the diabetes/periodontal disease connection. If you have a blog or use social media for your dental practice, we recommend sharing these images so your patients can learn more about how their oral [...]<br />
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<b><i>A very nice and informational brochure. Print it out for your patients or put it up on your wall. </i></b>Mathaihttp://www.blogger.com/profile/13394299451400249276noreply@blogger.com0tag:blogger.com,1999:blog-5584530988132149961.post-65466063750962737722012-12-05T18:12:00.001+05:302012-12-05T18:12:03.033+05:30Surgical Rehearsal Platform Makes Virtual Operations Possible (Interview)<a href="http://feedproxy.google.com/~r/Medgadget/~3/rTf807aAFac/surgical-rehearsal-platform-makes-virtual-operations-possible-interview.html">Surgical Rehearsal Platform Makes Virtual Operations Possible (Interview)</a>: <img alt="Surgical-Theater" height="201" src="http://medgadgetenglish.s3.amazonaws.com/wp-content/uploads//2012/12/Surgical-Theater-300x201.jpg" style="float: right; margin: 0 15px 15px 0;" title="Surgical-Theater" width="300" /><br />
Medicine is continuously learning from other fields, perhaps the best example being aviation. It is from aviation that we gained the benefits of <a href="http://www.medgadget.com/2010/10/teamwork_and_checklists_improve_surgical_outcomes.html">checklists</a>, <a href="http://www.medgadget.com/2011/12/lockheed-and-hopkins-team-up-hope-to-transform-the-icu.html">integrated</a> ICUs and ORs, and – most recently – simulators. The first computer-based flight simulators came out 50 years ago and only now are we getting up to speed in terms of developing systems that enable surgeons to rehearse operations in advance.<br />
This past June <em>Medgadget </em>met up with the <a href="http://www.medgadget.com/2012/06/surgical-theater-a-surgeons-simulator-video-interview-at-the-white-house.html">Surgical Theater</a> team at The White House and discussed how they are turning this vision into a reality – or, rather, the other way around. Their flagship product, the Selman Surgical Rehearsal Platform (SRP), allows surgeons to “pre-live the future” by practicing procedures on <em>their actual patients’</em> anatomies using pre-operative MRI and CT images. We heard from them recently because the SRP has reached a few milestones in the past six months, including its first purchase by University Hospitals (UH) Case Medical Center in Cleveland and submission for FDA approval.<br />
<a href="http://www.medgadget.com/2012/12/surgical-rehearsal-platform-makes-virtual-operations-possible-interview.html">Read More</a><br />
<div><a href="http://feeds.feedburner.com/~ff/Medgadget?a=rTf807aAFac:ZntskAC7GsY:yIl2AUoC8zA"><img border="0" src="http://feeds.feedburner.com/~ff/Medgadget?d=yIl2AUoC8zA" /></a> <a href="http://feeds.feedburner.com/~ff/Medgadget?a=rTf807aAFac:ZntskAC7GsY:qj6IDK7rITs"><img border="0" src="http://feeds.feedburner.com/~ff/Medgadget?d=qj6IDK7rITs" /></a> <a href="http://feeds.feedburner.com/~ff/Medgadget?a=rTf807aAFac:ZntskAC7GsY:gIN9vFwOqvQ"><img border="0" src="http://feeds.feedburner.com/~ff/Medgadget?i=rTf807aAFac:ZntskAC7GsY:gIN9vFwOqvQ" /></a></div><img height="1" src="http://feeds.feedburner.com/~r/Medgadget/~4/rTf807aAFac" width="1" />Mathaihttp://www.blogger.com/profile/13394299451400249276noreply@blogger.com0tag:blogger.com,1999:blog-5584530988132149961.post-33174008369043832472012-11-30T20:34:00.001+05:302012-11-30T20:34:20.403+05:30Vertical Augmentation of the Posterior Mandible<div dir="ltr" style="text-align: left;" trbidi="on">
Vertical augmentation of the posterior mandible remains challenging. A variety of approaches have been tried. Among them are:<br />
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<li>Short Implants</li>
<li>Vertical augmentation using block grafts (autogenous,alloplastic as well as xenogenic).</li>
<li>Vertical augmentation using tenting screws, and a mixture of autograft and bovine bone mineral covered with a titanium reinforced PTFE membrane barrier.This is quite popular.</li>
<li>Vertical augmentation as above but using the implants themselves as tenting screws.</li>
<li>Tilted implants where feasible.</li>
<li>Transverse placement to avoid the IAN.</li>
<li>Nerve repositioning/relocation.</li>
<li>Subperiosteal implants if the resorption is down to basal bone. Not commonly used currently due to the high rate of failure and complications, technique sensitivity and lack of validating studies.</li>
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Another technique which does not enjoy the popularity it deserves is the interpositional graft. As far as techniques go I would rate it as moderately difficult but the results are phenomenal and complications are few. This has also been popularised by Ole Jensen as the "smile osteotomy" in his book <a href="http://www.quintpub.com/display_detail.php3?psku=B4184#.ULhfKuQTH-Y" target="_blank">The Osteoperiosteal Flap</a></div>
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Here is an illustration from the book that illustrates the procedure</div>
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<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhCSeAnmI9G23uK2ZrE3Wh5Mu-UnaHXK536l1Zly4iVR3UyrMQnlYx9r1qVRmN0Av3f_3uo1_GBBPghMakYNjoZIZRXhS1O_tq2-BlbBl9rHR0AjfJrnOmgoaR0Gwi733yjx9HtmPxRiYI/s1600/Picture1.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="265" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhCSeAnmI9G23uK2ZrE3Wh5Mu-UnaHXK536l1Zly4iVR3UyrMQnlYx9r1qVRmN0Av3f_3uo1_GBBPghMakYNjoZIZRXhS1O_tq2-BlbBl9rHR0AjfJrnOmgoaR0Gwi733yjx9HtmPxRiYI/s320/Picture1.jpg" width="320" /></a></div>
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The case presented below differs in some respects.<br />
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<li>The interpositional graft used was a FDBA Bone Block from Tata Bone Bank in Mumbai not autogenous bone or particulate graft material..</li>
<li>No bone plates were used to stabilise the fragments. In some cases this may be necessary.</li>
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The "smile" osteotomy</div>
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<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjitxox3R-_Fk7VFRtnBUebj2Y37mpyRve2tMegUIJYNHVmG8kinPAhWAIw8pNy0F38qhKtrYcB9hjAuXPFJDVW9LEMdD6GXM7ep-Ke3fOcOjo-OxJjZpnW2fxx5AGi4r_WqDED8W4QZt8/s1600/slide+1.JPG" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="213" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjitxox3R-_Fk7VFRtnBUebj2Y37mpyRve2tMegUIJYNHVmG8kinPAhWAIw8pNy0F38qhKtrYcB9hjAuXPFJDVW9LEMdD6GXM7ep-Ke3fOcOjo-OxJjZpnW2fxx5AGi4r_WqDED8W4QZt8/s320/slide+1.JPG" width="320" /></a></div>
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Mobilising the the fragment vertically. Note that the coronal fragment is still pedicled to the lingual mucosa. The incision in the soft tissue is vestibular rather than crestal. One can use a bur, peizosurgery saw or oscillating saw for this cut..One can easily create a gap of 5 to 6mm or more using this technique. </div>
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<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEgVJwTTXEgjvoPihkv-mPcpuVmlQpNweXqYZOlDtvVGBYNeTfT6uxeG1oFrxqTwcG3l13TKX6mOVbVRPzCuAXg6MlZ9YI4_yynFljPatfeAogkZRWTekSLMJtKEW1_Sa0C7anf3LaaF1IM/s1600/slide+2.JPG" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="213" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEgVJwTTXEgjvoPihkv-mPcpuVmlQpNweXqYZOlDtvVGBYNeTfT6uxeG1oFrxqTwcG3l13TKX6mOVbVRPzCuAXg6MlZ9YI4_yynFljPatfeAogkZRWTekSLMJtKEW1_Sa0C7anf3LaaF1IM/s320/slide+2.JPG" width="320" /></a></div>
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Maintaining the gap with a graft: Here we have used a block of FDBA from the <a href="http://tmc.gov.in/medical/departments/as/tissue.htm" target="_blank">Tata Tissue Bank in Mumbai</a>. Alternatively one can use autograft harvested from the chin or ramus , or practically any kind of allograft or xenograft by itself or mixed with autograft. In case of particulate autograft it may be necessary to stabilise the coronal fragment with plates and screws. This may be needed even in case of block grafts if the fragments do not maintain position. </div>
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<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEiDruInBokRvL9vihpvodQzuAvXZA_r30PQiqrzUdq_0n_vTiTTZJHo4ePbj3Ssl34X5wdlAiK7YSP_EMcBa1D-9F5fBxq2gd2_ZwnNZiqf39CQSYxFwE6PZUEjX8BgZGdID0LRtTJXq7w/s1600/slide+4.JPG" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="213" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEiDruInBokRvL9vihpvodQzuAvXZA_r30PQiqrzUdq_0n_vTiTTZJHo4ePbj3Ssl34X5wdlAiK7YSP_EMcBa1D-9F5fBxq2gd2_ZwnNZiqf39CQSYxFwE6PZUEjX8BgZGdID0LRtTJXq7w/s320/slide+4.JPG" width="320" /></a></div>
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Three or four months later the graft is on its way to being replaced by the body's own bone and one can see the margins of the osteotomy have been bridged over. The increase in vertical height is evident.</div>
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<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjExiluEH-Hept6xDcVW_fPSAsgJFy0a8O32QYJFDf1P-7XkWP8ZaGpoHWTM1V2Hr4t5xEhdnnGC_k9DxdC-wqQIqlI4rEEZo5AD4PC4aHPVg2JuoRlIIc_LVkH4Qk-JJLRWvHmCgW05S4/s1600/slide+5.JPG" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="213" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjExiluEH-Hept6xDcVW_fPSAsgJFy0a8O32QYJFDf1P-7XkWP8ZaGpoHWTM1V2Hr4t5xEhdnnGC_k9DxdC-wqQIqlI4rEEZo5AD4PC4aHPVg2JuoRlIIc_LVkH4Qk-JJLRWvHmCgW05S4/s320/slide+5.JPG" width="320" /></a></div>
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Implants have been placed .</div>
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<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjC24Hvr8QjWrAnksP_cYxrrTWsSWLbCUIiR5Ktu7mGKyIGMwwIesYsfO9fq9EPTWHs3pIuYuDOOn8nh-cAPneB0uFx8QPsGbmkhHDhq7HX3Q_-0xRZGhObqwNX5QYcctIa0YsaBg3ah1w/s1600/slide+6.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="231" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjC24Hvr8QjWrAnksP_cYxrrTWsSWLbCUIiR5Ktu7mGKyIGMwwIesYsfO9fq9EPTWHs3pIuYuDOOn8nh-cAPneB0uFx8QPsGbmkhHDhq7HX3Q_-0xRZGhObqwNX5QYcctIa0YsaBg3ah1w/s320/slide+6.jpg" width="320" /></a></div>
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Mathaihttp://www.blogger.com/profile/13394299451400249276noreply@blogger.com0tag:blogger.com,1999:blog-5584530988132149961.post-69793515862294012142012-11-30T10:12:00.001+05:302012-11-30T10:12:34.998+05:30<div dir="ltr" style="text-align: left;" trbidi="on">
A Classic "Royally" treated<br />
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<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEh577hjXMHP6uS3oAAs5bJ2qtm1xIyHCwyc8paqGexLZDDb-kz7otBujsJR_u1rlOpXQSMpwNle7GWIymikLhInKD0GYGnWTjMjUs71iMnbrAey8BFVPhFJ0Ey8XUM4z8aCM5DqJWn9bMI/s1600/ami+parikh_001.JPG" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="165" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEh577hjXMHP6uS3oAAs5bJ2qtm1xIyHCwyc8paqGexLZDDb-kz7otBujsJR_u1rlOpXQSMpwNle7GWIymikLhInKD0GYGnWTjMjUs71iMnbrAey8BFVPhFJ0Ey8XUM4z8aCM5DqJWn9bMI/s320/ami+parikh_001.JPG" width="320" /></a></div>
What do you think of this "bed of Nails"?<br />
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Mathaihttp://www.blogger.com/profile/13394299451400249276noreply@blogger.com0tag:blogger.com,1999:blog-5584530988132149961.post-18437573398941284892012-11-27T10:53:00.001+05:302012-11-27T10:53:35.471+05:30Christensen pins implant makers !Upfront as always Gordon Christensen makes a strong point. Follow the link to this article in drbicuspid.com<br />
<a href="http://www.drbicuspid.com/index.aspx?sec=sup&sub=rst&pag=dis&itemId=311794&wf=1380" target="_blank">http://www.drbicuspid.com/index.aspx?sec=sup&sub=rst&pag=dis&itemId=311794&wf=1380</a><br />
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<a href="https://chrome.google.com/webstore/detail/pengoopmcjnbflcjbmoeodbmoflcgjlk" style="font-size: 13px;">'via Blog this'</a>Mathaihttp://www.blogger.com/profile/13394299451400249276noreply@blogger.com0tag:blogger.com,1999:blog-5584530988132149961.post-36410251072619277012012-11-14T14:10:00.001+05:302012-11-14T14:10:07.390+05:30Is Bruxism a Risk Factor for Dental Implants? A Systematic Review of the Literature<b>I haven't read the original study but the abstract seems interesting. The authors attempt to answer a question that we all have asked ourselves at some time or another. But we still don't have a useful classification system for Bruxism or Parafunction that allows us to categorise patients in some clinically relevant fashion.....</b><br />
<b>If someone has access to the original paper I would appreciate if you could mail it to me !</b><br />
<a href="http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1111%2Fcid.12015">Is Bruxism a Risk Factor for Dental Implants? A Systematic Review of the Literature</a>: <br />
<h3>Abstract</h3><div><h4>Purpose</h4><div>To systematically review the literature on the role of bruxism as a risk factor for the different complications on dental implant-supported rehabilitations.</div></div><div><h4>Material and Methods</h4><div>A systematic search in the National Library of Medicine's Medline Database was performed to identify all peer-reviewed papers in the English literature assessing the role of bruxism, as diagnosed with any other diagnostic approach (i.e., clinical assessment, questionnaires, interviews, polysomnography, and electromyography), as a risk factor for biological (i.e., implant failure, implant mobility, and marginal bone loss) or mechanical (i.e., complications or failures of either prefabricated components or laboratory-fabricated suprastructures) complications on dental implant-supported rehabilitations. The selected articles were reviewed according to a structured summary of the articles in relation to four main issues, viz., “P” – patients/problem/population, “I” – intervention, “C” – comparison, and “O” – outcome.</div></div><div><h4>Results</h4><div>A total of 21 papers were included in the review and split into those assessing biological complications (<em>n</em> = 14) and those reporting mechanical complications (<em>n</em> = 7). In general, the specificity of the literature for bruxism diagnosis and for the study of the bruxism's effects on dental implants was low. From a biological viewpoint, bruxism was not related with implant failures in six papers, while results from the remaining eight studies did not allow drawing conclusions. As for mechanical complications, four of the seven studies yielded a positive relationship with bruxism.</div></div><div><h4>Conclusions</h4><div>Bruxism is unlikely to be a risk factor for biological complications around dental implants, while there are some suggestions that it may be a risk factor for mechanical complications.</div></div>Mathaihttp://www.blogger.com/profile/13394299451400249276noreply@blogger.com0tag:blogger.com,1999:blog-5584530988132149961.post-65694228513488218052012-10-23T10:55:00.001+05:302012-10-23T10:55:21.906+05:30Something to think about !<a href="http://www.drbicuspid.com/index.aspx?sec=rca&sub=ada_2012&pag=dis&ItemID=311794&wf=1347">ADA News 2012 Conference</a>: <br />
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<a href="https://chrome.google.com/webstore/detail/pengoopmcjnbflcjbmoeodbmoflcgjlk" style="font-size: 13px;">'via Blog this'</a>Mathaihttp://www.blogger.com/profile/13394299451400249276noreply@blogger.com0tag:blogger.com,1999:blog-5584530988132149961.post-54825631075614525042012-07-02T12:20:00.002+05:302012-07-02T12:20:44.183+05:30Must See Video!<div dir="ltr" style="text-align: left;" trbidi="on">
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<iframe allowfullscreen='allowfullscreen' webkitallowfullscreen='webkitallowfullscreen' mozallowfullscreen='mozallowfullscreen' width='320' height='266' src='https://www.youtube.com/embed/2ZRfQK6Ipb0?feature=player_embedded' frameborder='0'></iframe></div>
A very dramatic representation of the difference in strength between a PFM and a ful contour zirconia crown. Worth watching !</div>Mathaihttp://www.blogger.com/profile/13394299451400249276noreply@blogger.com1tag:blogger.com,1999:blog-5584530988132149961.post-8287940595233915262012-05-10T13:59:00.001+05:302012-05-10T13:59:20.553+05:30Bone-to-implant contact after maxillary sinus floor augmentation with Bio-Oss and autogenous bone in different ratios in mini pigs<a href="http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1111%2Fj.1600-0501.2012.02438.x">Bone-to-implant contact after maxillary sinus floor augmentation with Bio-Oss and autogenous bone in different ratios in mini pigs</a>: <br />
<h3>Abstract</h3><div><h3>Objectives</h3><div>The objective was to test the hypotheses: (i) no differences in bone-to-implant contact formation, and (ii) no differences between the use of autogenous mandibular or iliac bone grafts, when autogenous bone, Bio-Oss mixed with autogenous bone, or Bio-Oss is used as graft for the maxillary sinus floor augmentation.</div></div><div><h3>Material and methods</h3><div>Bilateral sinus floor augmentation was performed in 40 mini pigs with: (A) 100% autogenous bone, (B) 75% autogenous bone and 25% Bio-Oss, (C) 50% autogenous bone and 50% Bio-Oss, (D) 25% autogenous bone and 75% Bio-Oss, or (E) 100% Bio-Oss. Autogenous bone was harvested from the iliac crest or the mandible and the graft composition was selected at random and placed concomitant with the implant placement. The animals were euthanized 12 weeks after surgery. Bone-to-implant contact was estimated by stereological methods and summarized as median percentage with 95% confidence interval (CI). Bone-to-implant contact formation was evaluated by fluorochrome labelling and assessed by median odds ratios (OR) with 95% (CI).</div></div><div><h3>Results</h3><div>Median bone-to-implant contact was: (A) 42.9% (95% CI: 32.1–54.5%), (B) 37.8% (95% CI: 27.1–49.9%), (C) 43.9% (95% CI: 32.6–55.9%), (D) 30.2% (95% CI: 21.6–40.3%), and (E) 13.9% (95% CI: 11.4–16.9%). Bone-to-implant contact was significantly higher for A, B, C, D as compared to E (<em>P </em>< 0.0001). Bone-to-implant contact was not significantly influenced by the ratio of Bio-Oss and autogenous bone (<em>P </em>= 0.19) or the origin of the autogenous bone (<em>P </em>= 0.72). Fluorochrome labelling revealed extensive variation in bone-to-implant contact formation over time. The labelling at weeks 2–3 was significantly increased with A compared to E (OR = 8.1 CI: 5.0–13.1, <em>P </em>< 0.0001), whereas E showed a significantly increased labelling at weeks 8–9 compared to A (OR = 0.5 CI: 0.3–0.7, <em>P </em>= 0.0028).</div></div><div><h3>Conclusions</h3><div>The hypothesis of no differences in bone-to-implant contact between the various treatment modalities was rejected since the bone-to-implant contact was significantly increased with autogenous bone or Bio-Oss mixed with autogenous bone as compared to Bio-Oss. Early bone-to-implant contact formation was more advanced with autogenous bone. No differences between the use of mandibular or iliac bone grafts were observed since the bone-to-implant contact was not significantly influenced by the origin of the bone graft.</div></div>Mathaihttp://www.blogger.com/profile/13394299451400249276noreply@blogger.com0tag:blogger.com,1999:blog-5584530988132149961.post-12506061574509307512012-05-10T13:54:00.001+05:302012-05-10T13:54:56.808+05:30Significance of keratinized mucosa around dental implants: a prospective comparative study<a href="http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1111%2Fj.1600-0501.2012.02475.x">Significance of keratinized mucosa around dental implants: a prospective comparative study</a>: <br />
<h3>Abstract</h3><div><h3>Objective</h3><div>The aim of this investigation was to evaluate the significance of keratinized mucosa (KM) around dental implants both clinically and biochemically for 12 months.</div></div><div><h3>Material and methods</h3><div>Fifteen edentulous patients treated with implant-retained overdentures in edentulous mandible (four implants per patient). Based on the presence of keratinized mucosa on the buccal surfaces, implants were divided into two groups: Implants having minimal 2 mm of KM on their buccal surfaces and implants having no KM on their buccal surfaces. Thirty-six implants were included in the evaluations; 19 implants in 15 patients had minimal 2 mm of KM on their buccal surfaces and 17 implants in 15 patients had no KM on their buccal surfaces. Clinical measurements of Plaque Index, Gingival Index, probing depths, and Bleeding on Probing were performed and peri-implant crevicular fluid (PICF) were collected immediately before loading (baseline) and at 6th, 12th months after loading. Interleukin-1 beta (IL-1 β) and tumor necrosis factor-alpha (TNF-α) have been assessed in the crevicular fluid. Results were analyzed by repeated-measures of variance (ANOVA) and Wilcoxon signed rank tests.</div></div><div><h3>Results</h3><div>After 12 months of evaluation the results of ANOVA showed that implants with KM had lower levels of TNF-α total amounts than implants without KM (<em>P</em> < 0.05). Additionally, TNF-α total amounts were significantly higher at 12<sup>th</sup> month compared to baseline for implants without KM (<em>P</em> < 0.05). Plaque index and Gingival index values were also found significantly higher for implants without KM (<em>P</em> < 0.05). For IL-1 β and PICF volume levels the differences between the implant groups were non significant, whereas the differences between the periods were significant. (<em>P</em> < 0.05) Additionally, both of the groups had higher levels of PII and BoP scores when compared to baseline (<em>P</em> < 0.05).</div></div><div><h3>Conclusions</h3><div>The results of this study showed that an adequate band of keratinized mucosa was related with less plaque accumulation and mucosal inflammation as well as pro-inflammatuar mediators, suggesting that it may be critical especially for plaque control and plaque associated mucosal lesions around dental implants.</div></div>Mathaihttp://www.blogger.com/profile/13394299451400249276noreply@blogger.com0tag:blogger.com,1999:blog-5584530988132149961.post-24953213018168575152012-04-01T11:20:00.001+05:302012-04-01T11:20:23.922+05:30These Silently Screaming Dental Mannequins Are What Nightmares Are Made Of [WTFriday]<a href="http://feeds.gawker.com/~r/gizmodo/full/~3/EagrgGTWKW4/">These Silently Screaming Dental Mannequins Are What Nightmares Are Made Of [WTFriday]</a>: <br />
<div style="float: left; padding-right: 10px;"><div><a href="http://gizmodo.com/5897839/these-silently-screaming-dental-mannequins-are-what-nightmares-are-made-of/gallery/" title="Click here to read These Silently Screaming Dental Mannequins Are What Nightmares Are Made Of"><br />
<img alt="Click here to read These Silently Screaming Dental Mannequins Are What Nightmares Are Made Of" height="120" src="http://img.gawkerassets.com/img/17i290pblbawnjpg/original.jpg" style="border-color: #b3b3b3; border-style: none solid solid; border-width: 0 1px 1px;" title="Click here to read These Silently Screaming Dental Mannequins Are What Nightmares Are Made Of" width="190" /><br />
</a></div></div>These synthetic heads don't need to be anywhere near the Uncanny Valley to be terrifying. Our friends at Oobject have assembled <a href="http://www.oobject.com/category/12-dental-training-heads/">12 of the creepiest prosthetic mouths in dentistry</a>. <a href="http://gizmodo.com/5897839/these-silently-screaming-dental-mannequins-are-what-nightmares-are-made-of/gallery/" title="Click here to read more about These Silently Screaming Dental Mannequins Are What Nightmares Are Made Of [WTFriday]">More »</a><br />
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<div><a href="http://feeds.gawker.com/~ff/gizmodo/full?a=EagrgGTWKW4:kAjl20xrJ7c:H0mrP-F8Qgo"><img border="0" src="http://feeds.feedburner.com/~ff/gizmodo/full?d=H0mrP-F8Qgo" /></a> <a href="http://feeds.gawker.com/~ff/gizmodo/full?a=EagrgGTWKW4:kAjl20xrJ7c:yIl2AUoC8zA"><img border="0" src="http://feeds.feedburner.com/~ff/gizmodo/full?d=yIl2AUoC8zA" /></a> <a href="http://feeds.gawker.com/~ff/gizmodo/full?a=EagrgGTWKW4:kAjl20xrJ7c:D7DqB2pKExk"><img border="0" src="http://feeds.feedburner.com/~ff/gizmodo/full?i=EagrgGTWKW4:kAjl20xrJ7c:D7DqB2pKExk" /></a> <a href="http://feeds.gawker.com/~ff/gizmodo/full?a=EagrgGTWKW4:kAjl20xrJ7c:V_sGLiPBpWU"><img border="0" src="http://feeds.feedburner.com/~ff/gizmodo/full?i=EagrgGTWKW4:kAjl20xrJ7c:V_sGLiPBpWU" /></a></div><img height="1" src="http://feeds.feedburner.com/~r/gizmodo/full/~4/EagrgGTWKW4" width="1" />Mathaihttp://www.blogger.com/profile/13394299451400249276noreply@blogger.com0tag:blogger.com,1999:blog-5584530988132149961.post-26876150145605574592012-04-01T10:56:00.001+05:302012-04-01T10:56:24.913+05:30Graphene Nanosensor Monitors Bacteria in Your Mouth<a href="http://feedproxy.google.com/~r/Medgadget/~3/xq_ctREVQjE/graphene-nanosensor-monitors-bacteria-in-your-mouth.html">Graphene Nanosensor Monitors Bacteria in Your Mouth</a>: <img alt="Graphene-based-wireless-bacteria-detection" height="255" src="http://cdn.medgadget.com/wp-content/uploads/2012/03/Graphene-based-wireless-bacteria-detection-300x255.jpg" style="float: right; margin: 0 15px 15px 0;" title="Graphene-based-wireless-bacteria-detection" width="300" /><br />
A team of scientists from Tufts University and Princeton University have developed a wireless bacteria detection technology which can be interfaced with a number of surfaces, including biological substrates, such as the enamel of a tooth. The researchers used graphene to achieve a very high degree of sensitivity. By printing the graphene onto water soluble silk, the sensor could then be easily transferred to biological surfaces. A patterned resonator coil design on the printed sensor acts as a passive antenna to enable power and wireless communication with the sensor.<br />
Most recently, the researchers have demonstrated their sensor by attaching it to a tooth for monitoring of respiration and bacteria detection in saliva.Their findings have been reported in the March 27 online edition of <em>Nature Communications</em>.<br />
<a href="http://medgadget.com/2012/03/graphene-nanosensor-monitors-bacteria-in-your-mouth.html">Read More</a><br />
<div><a href="http://feeds.feedburner.com/~ff/Medgadget?a=xq_ctREVQjE:OWdVIfYzy_Y:yIl2AUoC8zA"><img border="0" src="http://feeds.feedburner.com/~ff/Medgadget?d=yIl2AUoC8zA" /></a> <a href="http://feeds.feedburner.com/~ff/Medgadget?a=xq_ctREVQjE:OWdVIfYzy_Y:qj6IDK7rITs"><img border="0" src="http://feeds.feedburner.com/~ff/Medgadget?d=qj6IDK7rITs" /></a> <a href="http://feeds.feedburner.com/~ff/Medgadget?a=xq_ctREVQjE:OWdVIfYzy_Y:gIN9vFwOqvQ"><img border="0" src="http://feeds.feedburner.com/~ff/Medgadget?i=xq_ctREVQjE:OWdVIfYzy_Y:gIN9vFwOqvQ" /></a></div><img height="1" src="http://feeds.feedburner.com/~r/Medgadget/~4/xq_ctREVQjE" width="1" />Mathaihttp://www.blogger.com/profile/13394299451400249276noreply@blogger.com0tag:blogger.com,1999:blog-5584530988132149961.post-45600030063357429412012-03-23T13:09:00.001+05:302012-03-23T13:13:39.473+05:30New Gel May Mean No More Dental Anesthesia Shots - Science News - redOrbit<div dir="ltr" style="text-align: left;" trbidi="on">
<b>This seems exciting. It would definitelymake treatment more acceptable to many of our patients !</b><br />
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<a href="http://www.redorbit.com/news/science/1112493300/new-gel-may-mean-no-more-dental-anesthesia-shots/">New Gel May Mean No More Dental Anesthesia Shots - Science News - redOrbit</a>:<br />
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Anesthetic gel made from a rare plant found deep in the Peruvian rainforest has been found to be so potent that it could potentially replace the uncomfortable anesthetic injections used prior to dental procedures — and provide a natural remedy for aching teeth, scientists say.</div>
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The remarkable painkilling properties of the Acmella oleracea plant, commonly referred to as Spilanthes Extract, have been used for centuries if not millennia by Incas to treat toothache, ulcers, abscesses and to even clean teeth.</div>
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Indigenous tribes revealed the secrets of the plant to Cambridge University researcher Dr. Françoise Barbira Freedman, who has spent more than 30 years visiting and living with the Keshwa Lamas tribe of Peru. Freedman said the plant could literally transform western dental practice.</div>
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Freedman became the first westerner to be accepted into the secretive society in 1975. During one of her trips to the rainforest, she suffered severe pain in her wisdom teeth. She was given the remedy by the tribe‘s medicine men and the pain subsided “immediately,” she said.<b><a href="http://www.redorbit.com/news/science/1112493300/new-gel-may-mean-no-more-dental-anesthesia-shots/" target="_blank"> more</a></b></div>
<div id="clply-tag" style="background-color: #f6f6f6; border-bottom-width: 0px; border-color: initial; border-image: initial; border-left-width: 0px; border-right-width: 0px; border-style: initial; border-top-width: 0px; font-family: Arial, sans-serif; font: inherit; line-height: 18px; margin-bottom: 20px; outline-color: initial; outline-style: initial; outline-width: 0px; padding-bottom: 0px; padding-left: 0px; padding-right: 0px; padding-top: 0px; text-align: left; vertical-align: baseline;">
Source: <a href="http://s.tt/17lS9" style="background-attachment: initial; background-clip: initial; background-color: transparent; background-image: initial; background-origin: initial; background-position: initial initial; background-repeat: initial initial; color: #13539a; font-size: 10px; margin-bottom: 0px; margin-left: 0px; margin-right: 0px; margin-top: 0px; padding-bottom: 0px; padding-left: 0px; padding-right: 0px; padding-top: 0px; text-decoration: none; vertical-align: baseline;">redOrbit</a> (<a href="http://s.tt/17lS9" style="background-attachment: initial; background-clip: initial; background-color: transparent; background-image: initial; background-origin: initial; background-position: initial initial; background-repeat: initial initial; color: #13539a; font-size: 10px; margin-bottom: 0px; margin-left: 0px; margin-right: 0px; margin-top: 0px; padding-bottom: 0px; padding-left: 0px; padding-right: 0px; padding-top: 0px; text-decoration: none; vertical-align: baseline;">http://s.tt/17lS9</a>)</div>
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<a href="https://chrome.google.com/webstore/detail/pengoopmcjnbflcjbmoeodbmoflcgjlk" style="font-size: 13px;">'via Blog this'</a></div>Mathaihttp://www.blogger.com/profile/13394299451400249276noreply@blogger.com0tag:blogger.com,1999:blog-5584530988132149961.post-3423530158038786502012-03-01T14:05:00.000+05:302012-03-01T14:05:13.594+05:30Membrane Perforation in Sinus Floor Elevation – Piezoelectric Device versus Conventional Rotary Instruments for Osteotomy: An Experimental Study<div style="font-weight: normal; "><br /></div><div><b>It seems NOTHING , nothing is a substitute for knowledge, experience and expertise ! </b></div><div>A piezosurgery device is a very useful adjunct for doing sinus floor elevations. But it is not a magic wand that will make membrane perforations go away !</div><div style="font-weight: normal; "><br /></div><a href="http://dx.doi.org/10.1111%2Fj.1708-8208.2012.00447.x" style="font-weight: normal; ">Membrane Perforation in Sinus Floor Elevation – Piezoelectric Device versus Conventional Rotary Instruments for Osteotomy: An Experimental Study</a>: <h3 style="font-weight: normal; ">ABSTRACT</h3><div style="font-weight: normal; "><p><b>Purpose:</b> Sinus membrane perforation is the most common intraoperative complication of maxillary sinus floor elevation (MSFE) procedures and frequently causes postoperative problems. Piezoelectric devices have been claimed to reduce the frequency of membrane perforations although no clear evidence supports this view.</p></div><div style="font-weight: normal; "><p><b>Materials and Methods:</b> Ten surgeons with different expertise levels performed 80 MSFEs in selected lamb heads, with rotary and piezoelectric instruments following standard protocols. After the procedures, specimens were coded and perforations or tears determined through a microscope.</p></div><div style="font-weight: normal; "><p><b>Results:</b> No significant differences in terms of thickness either of the sinus lateral wall (<em>x<sub>i</sub></em>-<em>x<sub>j</sub></em> = 73.2; 95% confidence interval [CI] = 45.3–191.8) or the membrane (<em>x<sub>i</sub></em>-<em>x<sub>j</sub></em> = 24.2; 95% CI = −29.4 to 77.9) were identified between the specimens allocated to each group. Nine membrane perforations (11.2%) occurred during the study, all within the lower expertise group. Membrane elevation by hand instruments caused five perforations (40%) in the rotary instrument group and one in the piezoelectric group. Expert surgeons produced no membrane perforations, the size of the antrostomy that was smaller in the piezoelectric group being the only significant difference between the rotary and piezoelectric groups.</p></div><div style="font-weight: normal; "><p><b>Conclusions:</b> The use of piezoelectric material for MSFE reduces the frequency of membrane perforation among surgeons with a limited experience.</p></div>Mathaihttp://www.blogger.com/profile/13394299451400249276noreply@blogger.com0tag:blogger.com,1999:blog-5584530988132149961.post-74369995178801179232012-03-01T13:55:00.000+05:302012-03-01T13:55:55.440+05:30Soft Tissue Preservation and Pink Aesthetics around Single Immediate Implant Restorations: A 1-Year Prospective Study<div><br /></div><div>As one can see from the abstract below , even when the biotype is thick and buccal bone is intact achieving esthetic success with immediate implant placement in the esthetic zone is fraught with uncertainty. The protocol suggested by Buser and Belser for early placement after soft tissue healing is probably a safer protocol for most of us in clinical practice where predictability is key.</div><div><br /></div><div><br /></div><a href="http://dx.doi.org/10.1111%2Fj.1708-8208.2012.00448.x">Soft Tissue Preservation and Pink Aesthetics around Single Immediate Implant Restorations: A 1-Year Prospective Study</a>: <h3>ABSTRACT</h3><div><p><b>Purpose:</b> (1) To document soft tissue aspects using a specific protocol for immediate implant treatment (IIT) following single-tooth removal; (2) to evaluate whether this protocol allows preservation of pink aesthetics as objectively assessed.</p></div><div><p><b>Materials and Methods:</b> Patients with a thick gingival biotype and intact buccal bone wall upon extraction of a single tooth in the aesthetic zone (15–25) were consecutively treated. The protocol included flapless extraction and implant surgery, socket grafting, immediate nonocclusal loading with a screw-retained provisional crown, and replacement by a permanent crown 6 months thereafter. The outcome was assessed after 3, 6, and 12 months. Cases demonstrating major alveolar process remodeling and/or advanced midfacial recession (>1 mm) at 3 months were additionally treated with a connective tissue graft (CTG). The emergence profile of the provisional crown was replicated for all permanent crowns.</p></div><div><p><b>Results:</b> Twenty-two patients (12 men, 10 women; mean age 50) were treated after tooth extraction for nonperiodontal reasons using a novel bone condensing implant with variable-thread design, conical connection, and platform switch (NobelActive®, Nobel Biocare, Göteborg, Sweden). One implant failed and mean marginal bone loss was 0.1 mm (<em>p</em> = .059). Temporary mesial papilla reduction occurred, whereas distal papilla reduction was permanent (mean 0.5 mm; <em>p</em> = .001). At 3 months, five cases demonstrated major alveolar process remodeling and two advanced midfacial recession. Hence, slight initial decline in the pink esthetic score (PES) (<em>p</em> = .053) was observed. CTG resulted in a steady improvement of the PES after 3 months (<em>p</em> ≤ .037). At 12 months, pink aesthetics (mean PES 12.15) was comparable to the preoperative status (mean PES 11.86; <em>p</em> = .293). Distal papillae had significantly deteriorated (<em>p</em> = .020) in this time span, whereas midfacial contour had significantly improved (<em>p</em> = .005).</p></div><div><p><b>Conclusions:</b> Preservation of pink aesthetics is possible following IIT. However, to achieve that, CTG may be necessary in about one-third of the patients. Major alveolar process remodeling is the main reason for additional treatment.</p></div>Mathaihttp://www.blogger.com/profile/13394299451400249276noreply@blogger.com0tag:blogger.com,1999:blog-5584530988132149961.post-42244683493227273232012-02-24T11:08:00.000+05:302012-02-24T11:08:54.925+05:30A Novel Use for Biphosphonates !<div dir="ltr" style="text-align: left;" trbidi="on">
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<div id="contentstart" style="font-family: Arial, sans-serif; font-size: 13px; line-height: 15px; margin-bottom: 0px; margin-left: 0px; margin-right: 0px; margin-top: 0px; padding-bottom: 0px; padding-left: 0px; padding-right: 0px; padding-top: 0px; text-align: -webkit-auto;">
<table border="0" cellpadding="5" cellspacing="10" style="margin-bottom: 0px; margin-left: 0px; margin-right: 0px; margin-top: 0px; padding-bottom: 0px; padding-left: 0px; padding-right: 0px; padding-top: 0px;"><tbody style="margin-bottom: 0px; margin-left: 0px; margin-right: 0px; margin-top: 0px; padding-bottom: 0px; padding-left: 0px; padding-right: 0px; padding-top: 0px;">
<tr style="margin-bottom: 0px; margin-left: 0px; margin-right: 0px; margin-top: 0px; padding-bottom: 0px; padding-left: 0px; padding-right: 0px; padding-top: 0px;"><td align="center" class="style30" colspan="2" style="font-weight: 700; margin-bottom: 0px; margin-left: 0px; margin-right: 0px; margin-top: 0px; padding-bottom: 0px; padding-left: 0px; padding-right: 0px; padding-top: 0px;" width="600">A Bioactive Nanolayer for Orthopedic and Dental Implants</td></tr>
<tr style="margin-bottom: 0px; margin-left: 0px; margin-right: 0px; margin-top: 0px; padding-bottom: 0px; padding-left: 0px; padding-right: 0px; padding-top: 0px;"><td colspan="2" style="margin-bottom: 0px; margin-left: 0px; margin-right: 0px; margin-top: 0px; padding-bottom: 0px; padding-left: 0px; padding-right: 0px; padding-top: 0px;">(<em style="margin-bottom: 0px; margin-left: 0px; margin-right: 0px; margin-top: 0px; padding-bottom: 0px; padding-left: 0px; padding-right: 0px; padding-top: 0px;">Nanowerk News</em>) AddBIO AB, a subsidiary of Accelerator Nordic AB, has developed Zolidd®, a proprietary bioactive nanolayer for orthopedic and dental implants that releases bisphosphonate, a bone strengthening drug. A randomized clinical trial, conducted at Linköping University Hospital, Sweden, shows that dental implants with a bisphosphonate nanolayer have improved stability (see paper in <em style="margin-bottom: 0px; margin-left: 0px; margin-right: 0px; margin-top: 0px; padding-bottom: 0px; padding-left: 0px; padding-right: 0px; padding-top: 0px;">Bone</em>:<a href="http://dx.doi.org/doi:10.1016/j.bone.2012.02.001" rel="nofollow" style="color: blue; margin-bottom: 0px; margin-left: 0px; margin-right: 0px; margin-top: 0px; padding-bottom: 0px; padding-left: 0px; padding-right: 0px; padding-top: 0px; text-decoration: none;" target="new">"A bisphosphonate-coating improves the fixation of metal implants in human bone. A randomized trial of dental implants"</a>).</td></tr>
<tr style="margin-bottom: 0px; margin-left: 0px; margin-right: 0px; margin-top: 0px; padding-bottom: 0px; padding-left: 0px; padding-right: 0px; padding-top: 0px;"><td colspan="2" style="margin-bottom: 0px; margin-left: 0px; margin-right: 0px; margin-top: 0px; padding-bottom: 0px; padding-left: 0px; padding-right: 0px; padding-top: 0px;">Millions of people worldwide have dental implants, i.e. screws inserted to support artificial teeth. The first time after surgery, the implant is often not stable enough to enable chewing. It may take several months for the bone around the implant to heal and become strong enough for the patient to regain normal chewing function.</td></tr>
<tr style="margin-bottom: 0px; margin-left: 0px; margin-right: 0px; margin-top: 0px; padding-bottom: 0px; padding-left: 0px; padding-right: 0px; padding-top: 0px;"><td colspan="2" style="margin-bottom: 0px; margin-left: 0px; margin-right: 0px; margin-top: 0px; padding-bottom: 0px; padding-left: 0px; padding-right: 0px; padding-top: 0px;">"The study shows that local bisphosphonate improves implant stability, meaning that the time until normal chewing function could be shortened, thus reducing the suffering for the patient", says Professor Per Aspenberg, Linköping University Hospital, co-founder of AddBIO.</td></tr>
<tr style="margin-bottom: 0px; margin-left: 0px; margin-right: 0px; margin-top: 0px; padding-bottom: 0px; padding-left: 0px; padding-right: 0px; padding-top: 0px;"><td colspan="2" style="margin-bottom: 0px; margin-left: 0px; margin-right: 0px; margin-top: 0px; padding-bottom: 0px; padding-left: 0px; padding-right: 0px; padding-top: 0px;">Zolidd is the first application from a platform technology designed for local release of drugs from medical implants, developed by Professors Per Aspenberg and Penti Tengvall, Linköping University. A nanometer-thin protein layer is attached to the metal surface and a bisphosphonate is attached to the protein. When the bisphosphonate is released, a local effect is obtained, which improves implant stability. In the present study, a Zolidd prototype was used to release bisphosphonate in this way.</td></tr>
<tr style="margin-bottom: 0px; margin-left: 0px; margin-right: 0px; margin-top: 0px; padding-bottom: 0px; padding-left: 0px; padding-right: 0px; padding-top: 0px;"><td colspan="2" style="margin-bottom: 0px; margin-left: 0px; margin-right: 0px; margin-top: 0px; padding-bottom: 0px; padding-left: 0px; padding-right: 0px; padding-top: 0px;">Sixteen patients each received two implants, one with bisphosphonate and one without. After six months, the bisphosphonate treated implant showed improved stability in 15 out of 16 patients. On x-rays, the treated implants showed positive effects already after two months. No complications occurred.</td></tr>
<tr style="margin-bottom: 0px; margin-left: 0px; margin-right: 0px; margin-top: 0px; padding-bottom: 0px; padding-left: 0px; padding-right: 0px; padding-top: 0px;"><td colspan="2" style="margin-bottom: 0px; margin-left: 0px; margin-right: 0px; margin-top: 0px; padding-bottom: 0px; padding-left: 0px; padding-right: 0px; padding-top: 0px;">"This is an important study. With these results, we are now ready to take the next step in commercializing Zolidd", says Dr. Trine Vikinge, CEO AddBIO.</td></tr>
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<tr style="margin-bottom: 0px; margin-left: 0px; margin-right: 0px; margin-top: 0px; padding-bottom: 0px; padding-left: 0px; padding-right: 0px; padding-top: 0px;"><td colspan="2" style="margin-bottom: 0px; margin-left: 0px; margin-right: 0px; margin-top: 0px; padding-bottom: 0px; padding-left: 0px; padding-right: 0px; padding-top: 0px;">Source: <em style="margin-bottom: 0px; margin-left: 0px; margin-right: 0px; margin-top: 0px; padding-bottom: 0px; padding-left: 0px; padding-right: 0px; padding-top: 0px;">AddBIO (press release)</em></td></tr>
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</div>Mathaihttp://www.blogger.com/profile/13394299451400249276noreply@blogger.com0